| 1 | Kerron Clement | USA | |
47,91 | |
| 2 | Javier Culson | PUR | |
48,09 | NR |
| 3 | Bershawn Jackson | USA | |
48,23 | |
| 4 | Jehue Gordon | TRI | 48,26 | NR | |
| 5 | Periklís Iakovákis | GRE | 48,42 | ||
| 6 | Danny McFarlane | JAM | 48,65 | ||
| 7 | David Greene | GBR | 48,68 | ||
| 8 | Felix Sánchez | DOM | 50,11 |